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PtBio's Approach

  1. High-Precision Reference Genome Construction and Genomic Comparative Analysis:

    • Decode the complete genome sequence of target fish species (Yellowtail) with high precision using advanced sequencing technology, de novo assembly, and annotation analysis

    • Integrate genomic information from diverse traits to build a foundation for precision breeding

    • Efficiently detect genetic variations between individuals and lineages for use in breeding

  2. Optimization of Breeding Conditions:

    • Conduct detailed analysis of interactions between environmental factors and gene expression

    • Scientifically derive breeding conditions suitable for aquaculture environments

  3. Data-Driven Selective Breeding:

    • Combine on-site aquaculture technology with genomic analysis to derive optimal breeding strategies

    • Maximize the use of natural genetic diversity in aquatic organisms without genetic modification

    • Use genomic information-based individual selection to utilize artificially produced seedlings as next-generation broodstock

Background: Challenges Facing the Aquaculture Industry

  1. Climate Change and Food Resource Instability: Rising seawater temperatures and ocean acidification make stable supply difficult with conventional aquaculture methods.

  2. Limitations of Traditional Breed Improvement Methods: Adapting to changing environmental conditions has become increasingly difficult, requiring complementation with scientific methods.

  3. High Dependence on Wild Seedlings: Many farmed fish species depend on wild juveniles, making stable production difficult.

Project Outcomes and Social Impact

  1. Establishment of Selective Breeding Methods and Development of Functional Seedlings:

    • High-precision selection of superior individuals using genomic analysis

    • Efficient production of seedlings with targeted functions such as growth rate

  2. Securing Sustainable Food Resources:

    • Reduced dependence on natural resources and environmental impact reduction

    • Construction of aquaculture production systems that are sustainable for both people and the environment

  3. Realizing Climate Change-Adaptable Aquaculture:

    • Develop seedlings resistant to environmental changes such as climate change through data-driven breeding

    • Dramatically improve the stability and productivity of aquaculture

  4. Expansion to Diverse Sushi Ingredients:

    • Apply technology to various other fish species based on successful models with representative fish species

    • Enable stable procurement of high-quality sushi ingredients for food service businesses and trading companies

Through this project, PtBio establishes innovative approaches to seedling development and superior breed selection in aquaculture, contributing to the realization of scientifically-based sustainable aquaculture. We are confident that our technology presents a new pathway that opens the future of the aquaculture industry and represents a significant step toward solving global food problems.

Innovative Genomic Data Analysis Opens the Future of Aquaculture

FOOD & LIFE COMPANIES Inc. (FLC)　Marine Birth Inc.　Hiroshima University　Aquaculture Partner Companies

Food & Agriculture

Project Vision

PtBio utilizes advanced genomic analysis technology to deliver new value to the aquaculture industry. Our goal is to establish sustainable and efficient aquaculture systems through the selection of superior breeds based on scientific evidence and the development of seedlings with targeted functions.

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By combining the principles of natural selection with our proprietary bioinformatics technology "Bio-DX" in a unique approach called digital breeding, we achieve breeding that maximizes the inherent genetic diversity of aquatic organisms without genetic modification.

 

This project is advancing through collaboration with the following partners as a new model of industry-academia cooperation:

  • FOOD & LIFE COMPANIES Inc. (FLC): Food service operator managing Sushiro

  • Marine Birth Inc.: R&D organization jointly established by FLC and Takuyo Corporation

  • Hiroshima University: Academic institution leading advanced genomic research

  • Aquaculture Partner Companies: Experts in aquaculture technology

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